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Discoveries

Appanna Lab

  1. A-ketoglutarate, a novel anti-oxidant.
     
  2. The TCA cycle: a key participant in ROS homeostasis (production?detoxification).
     
  3. AI severely affects Fe-containing enzymes within the TCA cycle and disrupts the ETC.
     
  4. AI stimulates oxalate and phosphatidylethanolamine production; Implications: AI waste management
     
  5. Anaerobic respiration via NADH oxidase: LDH is not the only indicator.
     
  6. Metal pollutants - Rhizobium;
    1. dysfunctional exopolysaccharide;
    2. production, implication, diminishes nodulation, N2 fixation.
       
  7. Mn triggers dramatic increase in exopolysaccharide synthesis;
    Implications: commercial production of polysaccharides.
     
  8. Discovery of a new enzyme: aerobactin synthase (E.C. 6.3.2.27),