Research

Body: 

Chemistry

  1. Dr. Nelson Belzile
  2. Dr. François Caron (cross-appointed from the School of the Environment)
  3. Dr. M'hamed Chahma
  4. Dr. Yu-Wei Chen (adjunct professor, Dept, Chemistry-Biochemistry)
  5. Dr. Joy Gray-Munro
  6. Dr. Eduard Guerra (cross-appointed from the Bharti School of Engineering)
    • Expertise: Electrometallurgy;  Electrowinning; Hydrometallurgy; Leaching; Mineral Processing
    • Research program: Dr. Guerra's field of expertise can be broadly categorized as hydrometallurgy. He is primarily interested in reducing the energy requirements and environmental impacts of metal production. Currently, he is working on an alternative method to destroy cyanide from gold mill effluents, using an electrolytic cell equipped with manganese dioxide coated anodes, in order to make these solutions safe for discharge into the environment.  Until recently, his research largely focussed on examining the beneficial effects of adding Teflon beads as a reusable catalyst to provide high reaction rates while reducing acid generation during pressure oxidation of sulfide minerals.  Another notable past project involved research into the use of a group of relatively nontoxic sulfur containing organics  (often used as pharmaceuticals to treat heavy poisoning) to improve the performance of thiosulfate leaching of gold.
    • Selected papers:
  7. Dr. Hélène Joly
  8. Dr. Sabine Montaut
  9. Dr. Jeffrey Shepherd
  10. Dr. James Watterson (cross-appointed from the Dept. of Forensic Sciences)

 

Biochemistry

  1. Dr. Jeffrey Gagnon (cross-appointed from the Department of Biology, Laurentian University)
  2. Dr. Eric R. Gauthier
  3. Dr. Baoqing Guo (adjunct professor, Health Sciences North Research Institute)
  4. Dr. Robert Lafrenie (cross-appointed from Health Sciences North Research Institute)
  5. Dr. Carita Lannér (cross-appointed from the Northern Ontario School of Medicine)
  6. Dr. Alexander Moise (cross-appointed from the Northern Ontario School of Medicine)
  7. Dr. Abdel Omri​​​
    • Expertise: Antibiotics; Bacterial biofilms; Bacterial pathogens; Liposomes; Toxicology

    • Research program
      My research program is centered on the design, formulation, development and characterization of drug and vaccine delivery systems; particularly those based on liposomes. A special focus on the site-specific targeting, controlled release, drug resistance, pharmacokinetic, pharmacodynamic, metabolism and toxicity of free and liposome-encapsulated biological active agents. My main research interests are as follows:

      • Liposomal delivery of antisense oligonucleotides. Effect on P-glycoprotein function in multidrug resistant cells in vitro and in vivo studies. Cationic liposome formulations are used to promote the penetration of antisense oligonucleotides into the cell membrane and protect them from enzymatic degradation (nucleases).
      • Liposomal delivery of antimicrobial agents towards resistant bacterial pathogens: pulmonary and systemic infections. Construction of liposomes with high encapsulation efficiency, favorable antimicrobial release profile and enhanced bactericidal activity, to overcome the problem of bacterial resistance caused by low permeability of the bacterial cell envelope and by production of antimicrobial-inactivating enzymes.
      • Liposomal formulations of drugs and vaccine for oral delivery. Liposomes are used to protect the encapsulated agents from the harsh gastrointestinal milieu (low pH, phospholipases, and bile salts) and to enhance their absorption to the systemic circulation and to increase the efficacy of these agents while minimizing their frequency of administration. Special liposomal formulation will be prepared, characterized and assayed for their efficacy in vitro and in animal models.
    • Selected papers:

  8. Dr. Amadeo Parissenti​​​
  9. Dr. Stefan Siemann
  10. Dr. Alain Simard (cross-appointed from Health Sciences North Research Institute)
  11. Dr. Guangdong Yang